Is There a Link Between Gut Infections & Parkinson’s Disease?

Is There a Link Between Gut Infections & Parkinson’s Disease?

For some time now, gut health has been suspected to play a key role in chronic conditions. We now know that there is significant interaction between the body’s immune system and bacteria in the intestinal tract, and researchers have become increasingly interested in how the immune system ties into conditions such as Parkinson’s disease (PD). But how do these factors all connect?

The Potential Role of Gut Infections in Parkinson’s Disease

Emerging research suggests Parkinson’s disease could have an autoimmune component. Autoimmune conditions occur when the body’s immune system confuses healthy cells for pathogens and sets out to destroy them. A small percentage of PD cases are caused by mutations in genes that code for the proteins PINK1 and Parkin, which help clear out damaged mitochondria. Individuals with these mutations are more likely to develop PD before the age of 50.

Yet, when scientists removed PINK1 and Parkin from mice in a recent study, thereby giving them the same mutations linked to Parkinson’s disease in humans, they did not develop the disease. The research team theorized that factors other than these genetic mutations alone would likely be required for PD to develop. In particular, they believed exposure to specific germs could trigger Parkinson’s disease in individuals with this mutation.

To test this theory, the mice were exposed to E. coli. As the researchers suspected, they experienced PD-like symptoms later in life, along with a loss of dopaminergic neurons in the brain. This suggests that in individuals with certain genetic mutations, gut infections can trigger an immune system response which targets healthy cells.

What the Findings Mean

This research has also led scientists to the conclusion that in people without functioning PINK1 and Parkin, intestinal infections can trigger PD, thereby demonstrating a clear gut-brain connection in the disease. While this doesn’t suggest that all PD cases are autoimmune, it does pose the theory that there could be an immune system element in some cases. Although the mystery surrounding Parkinson’s disease still remains, this discovery points to an interplay between the gut, genetics, and brain, which may ultimately pave the way for further developments in the realm of treatment.

Reducing the Risk of MS: Could Red Meat Help

Reducing the Risk of MS: Could Red Meat Help

While researchers have been puzzled over the precise contributing factors behind Multiple Sclerosis (MS) for many years, it is widely believed that risk factors are both genetic and environmental. Recently, more evidence has been uncovered which points to the role of environmental factors, and specifically, diet, in a person’s likelihood of developing the condition. A new study on the influence of diet has been published in The Journal of Nutrition and indicates a link between red meat consumption and a reduced risk of first clinical diagnosis of central nervous system demyelination (FCD), a precursor to MS.

MS Risk & Red Meat Consumption: A Noteworthy Association

Researchers used data from more than 280 individuals who had experienced FCD, and more than 550 control participants who hadn’t. The participants were ranked according to a points-based diet score which measured how many servings of red meat they consumed as part of a Mediterranean diet. The scores of the people who consumed three or more servings of unprocessed red meat were found to have a reduced risk of FCD, compared to those who consumed two or fewer.

Why Could Red Meat Help?

According to one of the lead study researchers, the nutrients found in red meat, including omega-3 fatty acids, zinc, protein, potassium, vitamin D, and selenium, are all known to contribute to brain functioning. One critical component to the potential benefits is choosing high-quality meats, however. The research shows sources such as grass-fed beef are linked to the reduced risk, and the study participants largely maintained good eating patterns, as they followed a Mediterranean diet. This approach to eating is known to boost cardiovascular health and prioritizes the intake of healthy fats, vegetables, fruits, and whole grains, among other key components.

Who Do These Findings Affect?

The study findings show that for individuals who had a first-degree relative with MS, the risk would drop from 2 to 4% down to 1 to 2.5%. The greatest benefit is seen among individuals who have an identical twin with MS: for this population, the risk drops from 30 to 50% down to 14 to 32%. The findings also suggest that the more unprocessed red meat the individual consumes, the greater the reduction of risk may be.

Ultimately, the benefits of eating red meat appear to be greatest for the populations with a close relative with MS. It’s worth noting, however, that authorities such as the World Health Organization have issued warnings against red meat, and suggest that it could be carcinogenic to humans. Dietary modifications such as these should, therefore, be discussed with a doctor before being introduced into an individual’s daily routine.

The Best & Worst Halloween Candy to Satisfy Your Sweet Tooth

The Best & Worst Halloween Candy to Satisfy Your Sweet Tooth

We already know that eating candy all the time isn’t exactly a health-conscious choice. Most is processed and filled with added sugars, giving it a pretty low nutrition-to-calorie ratio. Yet, every diet should leave room to fulfill once-in-a-while cravings, and Halloween certainly qualifies as a special occasion. If you find yourself yearning for some sweets this October, don’t feel guilty about having a piece of candy. Instead, reach for one of the healthier varieties below, and try to pass on the rest.

The Healthiest Halloween Candy

While these snacks certainly wouldn’t be considered superfoods, they pack a more powerful nutritional punch compared to other options. Here are a few varieties to try:

Peanut M&Ms

M&Ms already have an advantage over other candies: since there are lots of them in a pack, you’re more likely to take your time enjoying them as your snack, thereby fulfilling your craving with just one fun-size portion. If the colorful candies are what you’re craving, go for the peanut variety: the nuts have protein and fiber, which can help keep you fuller longer. And, a fun-size pack clocks in at just 90 calories.

Reese’s Peanut Butter Cups

Reese’s lovers, rejoice: the famous cups make the list of more nutritional candies, thanks to the protein-rich peanut butter. Instead of reaching for the double-cup package, consider purchasing a bag of the single-cup varieties. One cup has 110 calories and 2.5 grams of protein, so it won’t derail your healthy eating habits. Plus, you can distribute the rest to any trick-or-treaters who stop by, as Reese’s are a favorite among kids, too!

Snickers

While you might think that the sugary caramel would land Snickers bars on the “bad” list, this candy is actually lower in sugar and higher in protein than most other types. Once again, we have peanuts to thank for the added nutrition. And, if you choose a fun-size bar, you can indulge in your chocolatey snack with just 80 calories and 9 grams of sugar.

 

The Least Healthy Halloween Candy

While no food has to be considered completely off-limits, be mindful when snacking on the candies below, as they fall at the very bottom of the list when it comes to nutrition.

Candy Corn

With a whopping 22 grams of sugar in just 15 pieces, candy corn defines “empty calories.” Most candy lovers won’t be too dismayed, however, as survey data shows this Halloween staple is actually one of the most hated varieties of the season. If you’re hungry for something sweet, you could have two Reese’s or Snickers for the amount of sugar in one serving of candy corn.

Airheads

Heavily processed, loaded with artificial flavors and coloring, and exceptionally sugary, there are many reasons why dentists loathe these sticky, nutritionally void candies. Not only do they leave you hungry for more since they have no protein or fiber, but they’re also likely to stick to your enamel, leaving you prone to tooth decay. If you just can’t shake the urge to have one, be sure to rinse and brush afterward.

Smarties

Another sugar-rich snack with empty calories, Smarties have carbohydrates and sugar but lack any meaningful nutrients like fiber or protein. Although one roll is only 25 calories, you’re better off getting your sugar fix with something that has a little more substance.

 

No matter which Halloween candy is your favorite, the best way to enjoy an indulgence this time of year is to do so without feeling bad about it. Halloween only comes once a year, so snack mindfully and remember to fill up on lean protein, plenty of veggies, and fresh fruit during other meals to balance out your diet. That way, you’ll make sure your body is getting all of the nutrition it needs, and there will be plenty of leeway for a piece of candy here or there.

Those with specific dietary needs, for example, those with Diabetes or considered Pre-Diabetes, should consult with their physician on any foods to ensure their health limits.

Could Alzheimer’s Be Linked to Gum Bacteria?

Could Alzheimer’s Be Linked to Gum Bacteria?

When it comes to chronic conditions like Alzheimer’s disease, experts are consistently exploring new research which could shed light on causative factors. The disease, as with many other serious illnesses, is believed to be caused by a combination of genetic, lifestyle, and environmental factors that impact the brain over time. Yet, researchers have recently discovered new findings involving gum bacteria and its potential role in Alzheimer’s, among other conditions.

The Brain-Mouth Connection

According to an article published in Experimental Biology, bacteria involved in gum disease is suspected to have the ability to travel throughout the body. The bacterium, Porphyromonas gingivalis, is the key agent behind periodontitis and is believed to exude toxins connected to Alzheimer’s disease, rheumatoid arthritis, and aspiration pneumonia. Samples of these bacteria were found in the brains of individuals with Alzheimer’s, and researchers used animal studies to demonstrate how the bacterium can make its way from the mouth to the brain.

The bacteria were more common in the brain samples of Alzheimer’s patients compared to people without the disease of roughly the same age. Its key toxins, called gingipains, were present in these individuals. Based on animal studies, it appears that the migration of the bacteria from the mouth to the brain can be stopped with chemicals that interact with gingipains.

The Critical Importance of Oral Care

Dentists have long urged patients to take caution against periodontitis, the most serious form of gum disease. Left unaddressed, it can lead to tooth loss and can damage the soft tissue and bone that support the teeth. Yet, experts now believe that it can also have body-wide effects. Previous research has suggested that it the bacteria that causes the disease could travel through the bloodstream and cause other conditions, such as coronary artery disease or stroke. These newest findings suggest that proper dental care is especially important for individuals with genetic risk factors for Alzheimer’s disease or Rheumatoid Arthritis.

While gum disease is common, it’s often preventable. Although genetic factors may play a role in a person’s likelihood for developing periodontitis, there are many controllable factors which can also be addressed. Avoiding or quitting smoking, brushing and flossing regularly, and having dental cleanings at least once per year are some of the most effective strategies for avoiding gum disease and its potential complications.

5 Plants That Help Control Joint Pain

5 Plants That Help Control Joint Pain

Joint pain and inflammation are common characteristics of arthritis. While many individuals use prescription medications to manage their discomfort, other lifestyle modifications such as dietary changes, regular exercise, and herbal supplements may help as well. In particular, certain herbs appear to minimize joint pain more so than others. Although clinical studies on the effectiveness of using the following herbal remedies for joint pain have been limited, the research that has been performed is promising. The following are 5 herbal remedies that may minimize joint pain:

Turmeric

The yellow spice commonly used in Indian food has an orange pulp within its stem, which is where the plant compound curcumin is housed. This powerful agent has demonstrated an ability to reduce chronic inflammation caused by rheumatoid arthritis. Yet, because the body can only absorb so much curcumin, its benefits may be limited.

Eucalyptus

Oils can be distilled from the eucalyptus plant and used for anti-inflammatory properties. They are also believed to hold antiviral and antibacterial benefits. The tannins and flavonoids within the leaves are antioxidants, which could help to minimize the joint inflammation and pain experienced in arthritis. Eucalyptus oil can be diffused or added to a warm bath, though many individuals have an allergy to the plant.

Frankincense

Hailing from the bark of the Boswellia tree, frankincense has an aromatic quality, making it a popular ingredient in perfumes and incense. It can be inhaled, applied directly to the skin, or taken as a supplement. The herb is also believed to prevent leukotrienes, the compounds responsible for inflammation. It has even been shown to be as effective as NSAIDs for addressing joint pain in conditions like osteoarthritis and rheumatoid arthritis, but with fewer side effects.

Aloe Vera

Aloe is often the plant that many people reach for to treat burns, as it has both anti-inflammatory and antimicrobial properties. Yet, its anti-inflammatory benefits can be realized by people with arthritis, too. The plant inhibits the production of inflammatory enzymes, which may help to control joint pain.

Borage Oil

The starflower plant contains seeds which are rich in an omega-6 fatty acid known as gamma-linolenic acid (GLA). When metabolized, GLA converts into a signaling molecule which helps regulate inflammatory responses within the body. Certain oils with GLA have been shown to alleviate pain in individuals with rheumatoid arthritis, but borage seed oil is believed to be the most effective because it protects cells from oxidative stress which could be caused by high concentrations of GLA.

While herbal remedies, unfortunately, cannot cure arthritis, they may make a noticeable difference in pain levels, swelling, and stiffness. For individuals who are seeking an alternative to NSAIDs or other drugs, trying plant-based alternatives may be a worthwhile therapeutic option to consider.

Can CBD Oil Combat Arthritis Pain?

Can CBD Oil Combat Arthritis Pain?

CBD oil has been appearing everywhere we look recently, and its popularity doesn’t seem to be disappearing any time soon. Known officially as cannabidiol, the compound is found in the marijuana plant and has been associated with a broad range of claims to boost health. Indeed, everything from promoting heart wellness to reducing acne has been credited to CBD oil — but is there really any evidence to back up these claims? While further research needs to be done to support many of these positions, one area that shows promise is CBD’s ability to relieve arthritis pain.

Arthritis: Common Yet Challenging

More than 54 million adults have been diagnosed with at least one type of arthritis, but it’s possible that there are many individuals living with the condition. Despite the fact that it’s very common, there is still no cure for arthritis, and it can be notoriously difficult to treat. Although medications are available for controlling symptoms, many have their own host of side effects. And, the pain caused by this joint condition can range from mildly uncomfortable to debilitating.

Where CBD Oil Comes In

CBD oil has the powerful ability to stimulate brain activity by interacting with cannabinoid receptor types 1 and 2, which are involved with the immune system, to decrease the effects of pain and inflammation. Yet, it doesn’t have the same psychoactive effects as marijuana and is thus considered a worthwhile alternative for arthritis patients seeking a natural solution without side effects for managing pain. The World Health Organization reports that CBD exhibits no indication of the potential for abuse or dependence and that there is no evidence of health-related issues resulting from pure CBD. But has it been proven effective for treating arthritis pain?

The research seems to say yes. In a study from the European Journal of Pain, topical CBD oil showed reduced inflammation and pain caused by arthritis. Research has also confirmed that CBD inhibits inflammatory and neuropathic pain, both of which are especially difficult to treat. In individuals with rheumatoid arthritis, controlled trials have shown that cannabis-medications can significantly improve pain, reduce inflammation, and improve quality of sleep.

If you’re experiencing chronic pain from arthritis, CBD could be the key to enjoying more pain-free days. Of course, quality is important to ensure optimal results, please visit our website to see available Charlotte’s Web products.

 

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